C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12N 15/861 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/92 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2430716
The present invention relates to nucleic acids corresponding to various exons of ABCA5, ABCA6, ABCA9, and ABCA10 genes as well as cDNAs encoding the novel full length of ABCA5, ABCA6, ABCA9, and ABCA10 proteins. The invention also relates to means for the detection of polymorphisms in general, and of mutations in particular, in the ABCA5, ABCA6, ABCA9, and ABCA10 genes or in the corresponding protein produced by the allelic form of the ABCA5, ABCA6, ABCA9, and ABCA10 genes.
La présente invention concerne des acides nucléiques correspondant à divers exons de gènes ABCA5, ABCA6, ABCA9 et ABCA10, ainsi que des ADN complémentaires codant toute la nouvelle longueur de protéines ABCA5, ABCA6, ABCA9 et ABCA10. La présente invention concerne également des systèmes permettant de détecter des polymorphismes, en général, et des mutations, en particulier, dans les gènes ABCA5, ABCA6, ABCA9 et ABCA10 ou dans la protéine correspondante, produite par la forme allélique des gènes ABCA5, ABCA6, ABCA9 et ABCA10.
Allikmets Rando
Arnould-Reguigne Isabelle
Dean Michael
Denefle Patrice
Duverger Nicolas
Aventis Pharma S.a.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Department Of Health And Human Services The Government Of The United States Of America Represented By Th
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