Amino acid sequences for therapeutical and prophylactic...

Details Amino acid sequences for therapeutical and prophylactic... Amino acid sequences for therapeutical and prophylactic...

C - Chemistry, Metallurgy

07

K

C07K 16/12 (2006.01) A61K 39/40 (2006.01) C07K 14/33 (2006.01) C12N 15/13 (2006.01) C12P 21/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2303202

The invention relates to monoclonal antibodies capable of recognizing and neutralizing epitopes from the ligand domain, the translocation domain or the catalytic domain for the enterotoxin (toxin A) and cytotoxin (toxin B) from clostrodium difficile, as well as their production and therapeutical and prophylactic applications to diseases due to said toxins.

La présente invention porte sur des anticorps monoclonaux capables de reconnaître et de neutraliser les épitopes du domaine des ligants, du domaine de la translocation ou du domaine catalytique de l'entérotoxine (toxine A) ou de la cytotoxine (toxine B) de clostridium difficile, ainsi que sur sa production et son application thérapeutique et prophylactique à l'égard des maladies causées par ces toxines.

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