C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/85 (2006.01) A61K 31/00 (2006.01) A61K 31/34 (2006.01) A61K 31/343 (2006.01) A61K 45/06 (2006.01) A61P 3/06 (2006.01) C07D 413/06 (2006.01)
Patent
CA 2491733
A class of benzodihydrofuran compounds having the structure of formula (I) below and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delaying the onset of or reducing the risk of conditions and sequelae that are associated with these diseases, such as atherosclerosis.
La présente invention concerne une classe de composés benzodihydrofurane possédant une structure représentée par la formule (I) ci-dessous et des sels de ceux-ci répondant aux normes pharmaceutiques. Ces composés conviennent comme composés thérapeutiques, en particulier dans le traitement de l'hyperlipidémie, de l'hypercholestérolémie, de la dyslipidémie et d'autres troubles lipidiques, et ces composés repoussent la survenue ou réduisent le risque de survenue de pathologies et de séquelles associées à ces maladie, telles que l'athérosclérose.
Shi Guo Q.
Zhang Yong
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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