Pharmaceutical composition including a corticosteroid and a...

A - Human Necessities – 61 – K

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Details

A61K 31/592 (2006.01) A61K 31/215 (2006.01) A61K 31/573 (2006.01) A61K 31/59 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2761039

A composition that includes a corticosteroid (e.g., betamethasone dipropionate), a vitamin D analog (e.g., calcipotriene) and an acyl ester of 1,2,3-trihydroxypropane or an ether thereof; and a method of treating a dermatologic condition (e.g., psoriasis vulgaris) in a mammal (e.g., human); are provided. The method includes topically administering to a mammal in need of such treatment an effective amount of the composition, to the affected topical area, for a period of time effective to treat the dermatologic condition.

La présente invention concerne une composition qui comprend un corticostéroïde (par exemple, le dipropionate de bétaméthasone), un analogue de vitamine D (par exemple, le calcipotriène) et un ester acylique de 1,2,3-trihydroxypropane ou un éther de celui-ci ; et un procédé de traitement d'une affection dermatologique (par exemple, le psoriasis vulgaire) chez un mammifère (par exemple, un humain). Le procédé comprend l'administration topique à un mammifère nécessitant un tel traitement d'une quantité efficace de la composition, dans la zone topique affectée, pendant une durée efficace pour traiter l'affection dermatologique.

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