Spiro-benzodioxoles and their use as cb1 antagonists

Details Spiro-benzodioxoles and their use as cb1 antagonists Spiro-benzodioxoles and their use as cb1 antagonists

C - Chemistry, Metallurgy

07

D

C07D 317/72 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2553970

The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5 and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof, for use as therapeutically active substances. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB 1 receptors.

La présente invention a trait à des composés de formule (I), dans laquelle R1, R2, R3, R4, R5 et X sont tels que définis dans la descriptions et les revendications, et leurs sels pharmaceutiquement acceptables, destinés à être utilisés en tant que substances d'activité thérapeutique. Les composés sont utiles pour le traitement et/ou la prophylaxie de maladies qui sont associées à la modulation des récepteurs CB1.

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