C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/72 (2006.01) A61K 31/44 (2006.01) C07D 211/74 (2006.01) C07D 211/78 (2006.01)
Patent
CA 2268756
Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
L'invention concerne de nouveaux composés. Ces composés comprennent généralement un groupe acide, un groupe basique, un groupe amino substitué ou N-acyle et un groupe possédant une fraction alkane éventuellement hydroxylée. Elle concerne également des compositions pharmaceutiques contenant ces composés inhibiteurs. Elle concerne également des procédés d'inhibition de neuramidinase dans des spécimens susceptibles de contenir neuraminidase. Elle concerne, de plus, des matériaux antigéniques, des polymères, des anticorps, des conjugués de ces composés comportant des marquages, ainsi que des procédés servant à détecter une activité de neuraminidase.
Kim Choung U.
Williams Matthew A.
Gilead Sciences Inc.
Robic
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