Novel mesenchymal progenitor cells derived from human...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2675313

The present invention relates to a novel mesenchymal human progenitor (hBS- MP) cell population derived from human blastocyst-derived stem (hBS) cells and the method to obtain the progenitor cell population in which is eliminated the need of co-culture steps, cell sorting, manual selection, and transfections. Furthermore, the present invention relates to the use of the hBS-MP cells in drug discovery and specifically for toxicity testings as well as for therapeutic use.

L'invention concerne une nouvelle population de cellules progénitrices mésenchymateuses humaines (hBS- MP) dérivées de cellules souches elles-mêmes dérivées de blastocystes humains (hBS) et un procédé destiné à obtenir une population de cellules progénitrices ne nécessitant pas d'étapes de co-culture, tri de cellules, sélection manuelle, ni transfections. En outre, cette invention concerne l'utilisation des cellules hBS-MP dans la recherche de médicaments et, plus particulièrement, dans les tests de toxicité ainsi que pour un usage thérapeutique.

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