Benzofuran derivative and pharmaceutical composition

Details Benzofuran derivative and pharmaceutical composition Benzofuran derivative and pharmaceutical composition

C - Chemistry, Metallurgy

07

D

C07D 307/80 (2006.01) A61K 31/34 (2006.01)

Patent

CA 2112890

ABSTRACT The present invention relates to a compound expressed by the following general formula (I), pharmacologically- acceptable salt thereof and pharmaceutical composition mainly comprising the same. Image [I] wherein R1 is hydrogen, halogen or alkyl R2 is alkoxycarbonyl, aralkyloxycarbonyl, carboxy, hydroxyalkyl or acyloxyalkyl: Y is >CHOH, >CHOZ, >CH2 or >CO; and z is acyl. The pharmaceutical composition of the present invention is effective for prevention and therapy of arteriosclerosis, ischemic heart diseases, cerebral infarction and restenosis after PTCA operations.

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