Vaccines containing non-live antigenic vectors

Details Vaccines containing non-live antigenic vectors Vaccines containing non-live antigenic vectors

A - Human Necessities

61

K

A61K 39/29 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2630547

The present invention provides a vaccine composition comprising a non-live vector which targets the MHC class I pathway derived from a bacterial toxin or an immunologically functional derivative thereof but excluding those which bind the Gb3 receptor complexed with at least one first antigen and further comprising at least one second antigen (which may be the same or different as the first antigen) and an adjuvant.

Cette invention concerne une composition vaccinale qui renferme un vecteur non vivant ciblant la voie du CMH de classe I dérivé d'une toxine bactérienne ou un dérivé immunologiquement fonctionnel de celui-ci mais qui exclue les vecteurs non vivants qui se lient au récepteur Gb3, sous forme de complexe avec au moins un premier antigène, et qui renferme également au moins un deuxième antigène (qui peut être identique au premier antigène ou différent de celui-ci) et un adjuvant.

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