C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/713 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 9/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2417671
The present invention relates to gene expression in normal cells and cells of malignant tumors and particularly to novel markers associated with cancer, Trp8, Trp9 and Trp10, and the genes encoding Trp8, Trp9 and Trp10. Also provided are vectors, host cells, antibodies, and recombinant methods for producing these human proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating a tumor.
L'invention concerne l'expression génique dans des cellules normales et des cellules de tumeurs malignes, et particulièrement les marqueurs Trp8, Trp9 et Trp10 associés au cancer, y compris les gènes codant ces marqueurs. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps et des procédés de recombinaison relatifs à l'élaboration des protéines humaines considérées. L'invention concerne enfin des procédés diagnostiques et thérapeutiques utiles pour le diagnostic et le traitement d'une tumeur.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Wissenbach Ulrich
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