Radiopharmaceuticals and methods for imaging

A - Human Necessities – 61 – K

Patent

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Details

A61K 51/00 (2006.01) A61K 49/00 (2006.01) A61K 51/12 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2273609

This invention discloses the concept of incorporating a radioactive agent and various dyes to enhance lymphatic drainage, sentinel and lymph nodes. The use of a gamma emitting radionuclide such as Tc-99m allows the localization of the lymph node(s) that allows the surgeon to initially plan the surgical procedure. On the day of the study the radiopharmaceutical may need to be injected imaged and with the skin marked externally to assist the surgeon in locating the node during surgery. In order to facilitate the surgical probe a gamma detecting surgical probe can assist in providing the relative location of the node. This procedure has been found to be useful, however it has often been difficult utilizing this procedure to find all of the nodes. This invention would incorporate the use of a radioactive probe with a dye, the addition of the dye into the particles would allow the physician to more rapidly identify lymphatic channels, sentinel and other node(s) and allow them to be excised which would dramatically reduce the surgical time for the patient.

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