Compositions and methods for inferring a response to a statin

Details Compositions and methods for inferring a response to a statin Compositions and methods for inferring a response to a statin

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C07H 21/00 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2486789

Methods for inferring a statin response of a human subject from a nucleic acid sample of the suject are provided, as are reagents such as oligonucleotide probes, primers, and primer pairs, which can be used to practice such methods. A method of inferring a statin response can be performed, for example, by identifying in a nucleic acid sample from a subject, a nucleotide occurrence of at least one statin response related single nucleotide polymorphism (SNP) and/or at least one statin response-related haplotype in a cytochrome P450 gene and/or and HMG Co-A reductase gene.

La présente invention concerne des méthodes permettant de déduire une réponse à la statine d'un sujet humain à partir d'un échantillon d'acide nucléique du sujet, que constituent les réactifs tels que les sondes, les amorces et les paires d'amorces oligonucléotidiques, qui peuvent être utilisées pour pratiquer de telles méthodes. Une méthode de déduction d'une réponse à la statine peut être mise en oeuvre, par exemple, par identification dans un échantillon d'acide nucléique d'un sujet, d'une occurrence de nucléotide d'au moins une réponse à la statine associée au polymorphisme de nucléotide simple (SNP) et/ou d'au moins un haplotype associé à la réponse à la statine dans un gène P450 cytochrome et/ou dans un gène de HMG Co-A réductase.

Affiliated with

Also associated with

Rating

Compositions and methods for inferring a response to a statin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for inferring a response to a statin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for inferring a response to a statin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1431981