Methods for modulating metabolic pathways of micro-organisms...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/81 (2006.01) C07K 14/395 (2006.01) C12N 1/16 (2006.01)

Patent

CA 2274150

The invention provides methods for changing the metabolic pathways of micro- organisms in the presence of a certain carbon source and uses of such changes, as well as micro-organisms and uses of such changes, as well as micro- organisms produced by these methods. In a preferred embodiment the invention provides new yeast strains with improved biomass yields, a process to obtain these yeasts and the potential application of these yeasts are provided. The biomass yield is improved by the introduction into a yeast of a DNA construct conferring altered expression of a gene encoding a protein controlling transcription of a number of glucose-repressed genes. The yeasts are less sensitive to glucose repression, resulting in an increase in respiratory capacity, reduction of ethanol production and increased conversion of sugar into biomass.

L'invention concerne des procédés servant à changer les mécanismes d'action métabolique de micro-organismes, en présence d'une certaine source de carbone, ainsi que des utilisations de tels changements. L'invention concerne également des micro-organismes et des utilisations de tels changements, de même que des micro-organismes produits à l'aide de ces procédés. Dans un mode de réalisation préféré de l'invention, on utilise des nouvelles souches de levure à rendements en biomasse améliorés. On décrit donc un procédé d'obtention de ces levures ainsi que de potentielles applications de celles-ci. On améliore le rendement en biomasse en introduisant, dans une levure, une construction d'ADN modifiant l'expression d'un gène codant pour une protéine régulant la transcription d'un certain nombre de gènes réprimés par glucose. Comme ces levures sont moins sensibles à la répression par le glucose, on obtient un accroissement de la capacité respiratoire, une diminution de la production d'éthanol et une conversion accrue du sucre en biomasse.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Methods for modulating metabolic pathways of micro-organisms... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for modulating metabolic pathways of micro-organisms..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for modulating metabolic pathways of micro-organisms... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1432650

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.