Coating prosthetic surfaces with mammalian cells

Details Coating prosthetic surfaces with mammalian cells Coating prosthetic surfaces with mammalian cells

C - Chemistry, Metallurgy

12

N

C12N 5/02 (2006.01) A61F 2/06 (2006.01) A61L 2/02 (2006.01) A61L 27/00 (2006.01) A61L 27/04 (2006.01) A61L 27/16 (2006.01) A61L 27/18 (2006.01) A61L 27/28 (2006.01) A61L 27/38 (2006.01)

Patent

CA 2082176

ABSTRACT OF THE DISCLOSURE A method of coating a prosthetic surface with mammalian cells is disclosed involving placing against the prosthetic surface a composition comprising a substance causing directed growth of endothelial cells and contacting the prosthetic surface, having the composition placed against it, with tissue or a physiological fluid, the tissue or physiological fluid containing mammalian cells, under conditions suitable for the mammalian cells to coat the prosthetic surface. The invention also includes a prosthesis with a surface coated as above with mammalian cells, as well as method of treating mammals by implanting the above-described prosthesis.

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