Antisense modulation of pi3k p85 expression

Details Antisense modulation of pi3k p85 expression Antisense modulation of pi3k p85 expression

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A01N 43/04 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12P 19/34 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2378227

Antisense compounds, compositions and methods are provided for modulating the expression of PI3K p85. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PI3K p85. Methods of using these compounds for modulation of PI3K p85 expression and for treatment of diseases associated with expression of PI3K p85 are provided.

L'invention porte sur des composés antisens, des compositions et des procédés utilisés dans la modulation de l'expression de PI3K p85. Les compositions comprennent des composés antisens, notamment des oligonucléotides antisens, ciblés sur les acides nucléiques codant PI3K p85. L'invention porte égalemtn sur des procédés d'utilisation de ces composés de modulation de l'expression de PI3K p85 et sur des procédés de traitement de maladies associées à l'expression de PI3K p85.

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