Induction of ctl responses to foreign antigens expressed in...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) C07K 14/16 (2006.01)

Patent

CA 2110682

2110682 9221376 PCTABS00017 A method of inducing a CTL response in an animal which comprises administering to the animal mycobacteria transformed with at least one DNA sequence which encodes a protein or peptide or fragment or derivative thereof which includes an epitope which is recognized by cytotoxic T lymphocytes. The mycobacteria are administered in an amount effective to induce a CTL response in an animal. In one embodiment, the transforming DNA sequence may encode an HIV protein or fragment or derivative thereof.

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