C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/30 (2006.01) C07D 405/04 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2407796
The present invention relates to a novel 3-hydroxychromen-4-one derivative of formula (1), pharmaceutically acceptable salt, hydrate, solvate or isomer thereof which is useful as an inhibitor for Cyclin Dependent Kinase ("CDK"); to a process for preparing the compound of formula (1); and to a composition for suppression or treatment of cancer and diseases induced by cell proliferation such as inflammation, angiostenosis, angiogenesis, etc. comprising the compound of formula (1) as an active component together with pharmaceutically acceptable carriers.
La présente invention concerne un dérivé de 3-hydroxychromèn-4-un représenté par la formule (1), ainsi qu'un sel, un hydrate, un solvate ou un isomère de ce dérivé, qui conviennent bien comme inhibiteur de la kinase dépendante des cyclines ("CDK"). L'invention concerne également un procédé d'obtention du composé de formule (I) et une composition permettant de guérir ou de traiter un cancer et des maladies dues à une prolifération cellulaire telle que l'inflammation, l'angiosténose, l'angiogenèse, etc. qui renferme le composé selon la formule (1) en tant que principe actif ainsi que des excipients pharmaceutiquement acceptables.
Choi Sei Hyun
Chung Hyun Ho
Hong Chang Yong
Jeong Shin Wu
Kim Dong Myung
Lg Life Sciences Ltd.
Robic
LandOfFree
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