C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2230127
The present invention relates to the identification and cloning of a novel neutralizing human monoclonal antibody to the Respiratory Syncytial Virus. The invention provides such antibodies, fragments of such antibodies retaining RSV- binding ability, chimeric antibodies retaining RSV-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Finally, the invention provides for diagnostic and therapeutic methods employing the antibodies and nucleic acids of the invention.
La présente invention concerne l'identification et le clonage d'un nouvel anticorps monoclonal neutralisant dirigé contre le Virus Respiratoire Syncytial (RSV). L'invention concerne également de tels anticorps, des fragments de tels anticorps conservant une aptitude à la liaison avec les RSV, des anticorps chimériques conservant une aptitude à la liaison avec le RSV, et des compositions pharmaceutiques incluant de tels anticorps. L'invention concerne en outre des acides nucléiques isolés codant les anticorps de l'invention et des cellules hôtes transformées par ce moyen. L'invention concerne enfin des procédés de diagnostic et de traitemet mettant en oeuvre les anticorps et les acides nucléiques de l'invention.
Gilmour Page S.
Pilkington Glenn R.
Borden Ladner Gervais Llp
Intracel Corporation
LandOfFree
Neutralizing monoclonal antibodies to respiratory syncytial... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Neutralizing monoclonal antibodies to respiratory syncytial..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neutralizing monoclonal antibodies to respiratory syncytial... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1436987