C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/40 (2006.01) A61K 39/187 (2006.01) C07K 14/18 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2071016
A method for detecting infection of a blood sample by a bovine diarrhoea virus (BVD). The method comprises a first test for the detection of anti-BVD antibodies and a second test for the detection of viral particles. The tests are characterised in that the anti-p80 antibodies are detected by means of a recombinant antigen comprising the HVD virus protein p80 produced in a eukaryotic host, and in that the presence of viral particles is detected by means of antibodies directed against the BVD virus protein p80, for the detection of persistent viremiae and acute infections by any BVD strain. Also within the scope of the invention is a nucleotide sequence corresponding to the BVD Osloss sequence encoding the non-structural protein p80 and a recombinant protein corresponding to the translation of this nucleotide sequence.
Chappuis Gilles-Emile
Lecomte Corine Martine Therese Ghislaine
Pin Jean-Jacques
Vandenbergh Danielle Marie Helene Jeanne
Merial Societe Par Actions Simplifiee
Rhone Merieux
Smart & Biggar
Societe Europeene de Biotechnologie
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