Heterobifunctional polymeric bioconjugates

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 65/333 (2006.01) A61K 31/785 (2006.01) A61K 47/48 (2006.01) A61K 51/06 (2006.01) C07K 17/08 (2006.01)

Patent

CA 2517459

Heterobifunctional polymeric prodrug platforms for delivering biologically active compounds, including proteins, monoclonal antibodies and the like are disclosed. One preferred compound is formula (I). Methods of making and using the compounds and conjugates described herein are also provided.

L'invention concerne des plates-formes de promédicaments polymères hétérobifonctionnels permettant de distribuer des composés biologiquement actifs, notamment des protéines, des anticorps monoclonaux et analogues. Un composé préféré est représenté par la formule (I). L'invention concerne également des procédés de production et d'utilisation des composés et des conjugués décrits.

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