Methods for diagnosing and treating cerebrovascular events...

G - Physics – 01 – N

Patent

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G01N 33/53 (2006.01)

Patent

CA 2610833

Methods and kits for diagnosing and treating cerebrovascular events, and for defining the time and anatomical location of an event, are provided based on the detection and quantification of bound or total and unbound NR2 peptides in biological fluids. The methods are optionally performed in conjunction with neurological scoring and neuroimaging, and are directed to risk assessment, prognosis, diagnosis and treatment of TIA and stroke on an emergency basis in the emergency room.

La présente invention concerne des méthodes et des trousses de diagnostic et de traitement des événements cérébrovasculaires, également utilisées pour définir le moment et la position anatomique d'un événement. Ces méthodes et ces trousses reposent sur la détection et la quantification des peptides NR2 liés ou des peptides totaux non liés présents dans les fluides biologiques. Les méthodes sont facultativement mises en oeuvre de manière conjointe à l'évaluation neurologique et à la neuroimagerie et visent à évaluer le risque, à poser le pronostic, le diagnostic et à définir le traitement de l'accident ischémique transitoire et de l'accident vasculaire cérébral sur une base d'urgence dans une salle d'urgence.

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