Nanocrystalline magnetic iron oxide particles, processes for...

Details Nanocrystalline magnetic iron oxide particles, processes for... Nanocrystalline magnetic iron oxide particles, processes for...

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 9/127 (2006.01) A61K 9/50 (2006.01) A61K 33/26 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61K 49/06 (2006.01) A61K 49/18 (2006.01) A61K 51/12 (2006.01) B01J 13/02 (2006.01) C08K 9/04 (2006.01)

Patent

CA 2068632

Novel nanocrystalline magnetic particles are provided herein which consist of a magnetic iron oxide core of Fe3 0 4, gamma-Fe2 0 3 or mixtures thereof, and an envelope chemisorbed to the core. The composition of the coating material comprises natural or synthetic glycosaminoglycans and/or their derivatives with molecular weights of 500 Da to 250,000 Da, if necessary, which have been covalently cross-linked with appropriate cross-linking agents and/or modified by specific additives. Processes for preparation of these particles as well as the use thereof in medical diagnostics and/or therapy are also taught.

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