C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) C12N 5/0784 (2010.01) A61K 38/00 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C07K 14/82 (2006.01)
Patent
CA 2694011
Provided are compositions and methods for treating survivin expressing cancers. The compositions contain peptide survivin peptide mimics with improved MHC-I binding characteristics. The method involves administering a survivin peptide mimic with improved MHC-I binding characteristics to an individual to effect inhibition of the growth of survivin expressing cancer cells in the individual.
La présente invention concerne des compositions et des procédés de traitement de cancers exprimant la survivine. Les compositions contiennent des mimétiques peptidiques de peptide de survivine présentant des caractéristiques de liaison avec MHI-i améliorées. Le procédé consiste à administrer un mimétique peptidique de survivine présentant des caractéristiques de liaison avec MHI-i améliorées à un individu afin d'inhiber la croissance de cellules cancéreuses exprimant la survivine chez l'individu.
Ciesielski Michael
Fenstermaker Robert A.
Health Research Inc.
Ridout & Maybee Llp
LandOfFree
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