Mitotic kinesin inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4245 (2006.01) C07D 271/107 (2006.01)

Patent

CA 2576057

The present invention relates to oxadiazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

L'invention concerne des oxadiazoles utilisés pour traiter les maladies prolifératives cellulaires et les troubles associés à l'activité de la kinésine KSP, et pour inhiber cette activité. L'invention concerne également des compositions comprenant les composés et leurs méthodes d'utilisation pour traiter le cancer chez les mammifères.

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