Vertebrate smoothened proteins

Details Vertebrate smoothened proteins Vertebrate smoothened proteins

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2267181

Novel vertebrate homologues of Smoothened, including human and rat Smoothened, are provided. Compositions including vertebrate Smoothened chimeras, nucleic acid encoding vertebrate Smoothened, and antibodies to vertebrate Smoothened, are also provided.

L'invention concerne de nouveaux homologues de protéines "Smoothened" de vertébrés, y compris des protéines "Smoothened" humaines et murines. L'invention concerne également des compositions comprenant des chimères de protéines "Smoothened" de vertébrés, un acide nucléique codant des protéines "Smoothened" de vertébrés, et des anticorps contre des protéines "Smoothened" de vertébrés.

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