Heteroarylpiperidine modulators of chemokine receptor activity

Details Heteroarylpiperidine modulators of chemokine receptor activity Heteroarylpiperidine modulators of chemokine receptor activity

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/4523 (2006.01) C07D 401/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2502178

The present invention is directed to compounds of the formula (I): (wherein R1, R2, R3, R4, R5, R6, R10 and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

L'invention concerne des composés de formule (I), dans laquelle R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6?, R¿10? et n sont spécifiés dans la description. Lesdits composés sont utilisés en tant que modulateurs de l'activité de récepteurs de la chimiokine. En particulier, lesdits composés sont utilisés en tant que modulateur du récepteur de la chimiokine CCR-2.

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