Nitrogen-containing aromatic derivatives

Details Nitrogen-containing aromatic derivatives Nitrogen-containing aromatic derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 9/10 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 43/00 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2488739

Compounds represented by the following general formula, salts thereof, or hydrates of both: wherein X1 is nitrogen or a group represented by the general formula: -CR10=; X2 is nitrogen or a group represented by the general formula: -CR11=; Y is oxygen or the like; R1 is C1-6 alkoxy, optionally substituted C6- 10 aryloxy, a group represented by the general formula: -NR12aR12b, or the like; R2 is hydrogen, optionally substituted C1-6 alkyl, or the like; R3, R4, R5, R6, R7, R8, R10, and R11 are each independently hydrogen, halogeno, optionally substituted C1-6 alkyl, or the like; R9 is a group represented by the general formula: -NR16aR16b, or the like; and R12a, R12b, R16a, and R16b are each independently hydrogen, optionally substituted C1-6 alkyl, or the like.

Composés de formule générale (I), ou sels desdits composés, ou hydrates des deux, dans laquelle X¿1? représente azote ou un groupe de formule générale CR¿10?=, X¿2? représente azote ou un groupe de formule générale CR¿11?=, Y représente oxygène ou analogue, R¿1? représente alcoxy C¿1-6?, aryloxy C¿6-10? éventuellement substitué, un groupe de formule générale NR¿12a?R¿12b?, ou analogue, R¿2? représente hydrogène, alkyle C¿1-6? éventuellement substitué ou analogue, R¿3?, R¿4?, R¿5?, R¿6?, R¿7?, R¿8?, R¿10? et R¿11? représentent chacun indépendamment hydrogène, halogéno, alkyle C¿1-6? éventuellement substitué ou analogue, R¿9? représente un groupe de formule générale NR¿16a?R¿16b?, ou analogue et R¿12a?, R¿12b?, R¿16a? et R¿16b? représentent chacun indépendamment hydrogène, alkyle C¿1-6? éventuellement substitué, ou analogue.

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