C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/19 (2006.01) C12P 7/40 (2006.01) C12P 7/64 (2006.01)
Patent
CA 2526935
The present invention relates to methods for the production of .omega.-3 and/or .omega.-6 fatty acids in oleaginous yeast. Thus, desaturases and elongases able to catalyze the conversion of linoleic acid (LA) to .gamma.- linolenic acid (GLA); .alpha.-linoleic acid (ALA) to stearidonic acid (STA); GLA to dihomo-.gamma.- linoleic acid (DGLA); STA to eicosatetraenoic acid (ETA); DGLA to arachidonic acid (ARA); ETA to eicosapentaenoic acid (EPA); DGLA to ETA; EPA to docosapentaenoic acid (DPA); and ARA to EPA have been introduced into the genome of Yarrowia for synthesis of ARA and EPA.
La présente invention concerne des procédés de production d'acides gras ?-3 et/ou ?-6 dans une levure oléagineuse. Ainsi, des désaturases et des élongases pouvant catalyser la conversion de l'acide linoléique (LA) en acide ?-linolénique (GLA) ; l'acide a-linoléique (ALA) en acide stéaridonique (STA) ; le GLA en acide dihomo-?- linoléique (DGLA) ; le STA en acide éicosatétraénoïque (ETA) ; le DGLA en acide arachidonique (ARA) ; l'ETA en acide éicosapentaénoïque (EPA) ; le DGLA en ETA ; l'EPA en acide docosapentaénoïque (DPA) ; et l'ARA en EPA ont été introduites dans le génome de la Yarrowia afin de synthétiser l'ARA et l'EPA.
Picataggio Stephen K.
Yadav Narendra S.
Zhu Quinn Qun
E.i. Du Pont de Nemours And Company
Torys Llp
LandOfFree
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