Anti-egfr antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/485 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2629095

The present invention encompasses EGFR specific monoclonal antibodies, or antigen-binding portions thereof. These antibodies, or antigen-binding portions thereof, have high affinity for EGFR, inhibit the activation of EGFR, and are useful for the treatment of EGFR mediated cancers.

La présente invention concerne des anticorps monoclonaux spécifiques au récepteur du facteur de croissance épidermique (EGFR) ou leurs parties de liaison à l~antigène. Ces anticorps, ou leurs parties de liaison à l~antigène, présentent une forte affinité à l~EGFR, inhibent l~activation de l~EGFR et se révèlent utiles lors du traitement des cancers induits par l~EGFR.

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