Hydantoin and succinimide-substituted derivatives of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/12 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/675 (2006.01) C07D 207/416 (2006.01) C07D 295/26 (2006.01) C07D 401/14 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 471/10 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2151821

Compounds of formula (I) where X is (a) or (b), R is Het, wherein Het is as defined in the description. These compounds are oxytocin and vasopressin antagonists useful in the treatment of preterm labor, dysmenorrhea, and for the stoppage of labor preparatory to cesarean delivery, timing of parturition, uterine hyperactivity, endometriosis, hypertension, congestive heart failure, hyponatremia and cognitive disorders.

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