Transdermal therapeutic system with protection against...

A - Human Necessities – 61 – K

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A61K 9/70 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2198092

A transdermal therapeutic system (TTS) comprising an active substance which is sensitive to hydrolysis, and having a layer-like structure comprising a backing layer impermeable to moisture and active substance, a matrix comprising the active substance, and optionally a protective layer covering the matrix is characterised in that the matrix contains a water-binding component.

L'invention concerne un système thérapeutique transdermique (TTS) comprenant un principe actif sensible à l'hydrolyse et une couche dorsale imperméable à l'humidité et au principe actif, qui présnte une structure en couches, ainsi qu'une matrix contenant le principe actif et, le cas échéant, une couche protectrice qui recouvre la matrice. Ce système thérapeutique transdermique se caractérise en ce que la matrice contient un constituant hygroscopique.

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