Intermediate compound which is used for the preparation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/55 (2006.01) A61K 31/44 (2006.01) A61P 3/10 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2525190

The invention relates to a compound having formula (IV), which is an intermediate compound that is used for the preparation of pioglitazone. The invention also relates to a method of obtaining the novel compound (IV) from a natural product, L-tyrosine, in which the amino group, in the form of an imino- aromatic group, is protected. The invention further relates to a method of obtaining pioglitazone from the aforementioned intermediate compound.

La présente invention se rapporte à un composé de formule (IV) qui est un intermédiaire utilisé pour la préparation de pioglitasone. L'invention se rapporte également à un procédé d'obtention du nouveau composé (IV) à partir d'un produit naturel, L-tyrosine, dans lequel le groupe aminé sous forme de groupe imino-aromatique est protégé, et à un procédé d'obtention de pioglitasone à partir dudit intermédiaire.

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