Anti-angiogenic peptides from the n-terminus of endostatin

Details Anti-angiogenic peptides from the n-terminus of endostatin Anti-angiogenic peptides from the n-terminus of endostatin

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/10 (2006.01) A61K 38/39 (2006.01) A61K 48/00 (2006.01) C07K 7/08 (2006.01) C07K 14/78 (2006.01)

Patent

CA 2537179

Provided herein are anti-angiogenic comprising the N-terminal end of endostatin, nucleic acids encoding the same, pharmaceutical preparations comprising an effective amount of the peptide and nucleic acids and use of the pharmaceuticals in treating or preventing diseases or conditions associated with undesirable angiogenesis.

L'invention concerne des anti-angiogéniques comprenant une extrémité N-terminale d'endostatine, des acides nucléiques codant pour celle-ci, des préparations pharmaceutiques contenant une quantité efficace du peptide et des acides nucléiques et l'utilisation des préparations pharmaceutiques dans le traitement ou la prévention des maladies ou états associés à une angiogenèse indésirable.

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