Method for treating hepatitis c virus infection in treatment...

A - Human Necessities – 61 – K

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Details

A61K 38/21 (2006.01) A61K 38/19 (2006.01) C07K 14/555 (2006.01) C07K 14/56 (2006.01)

Patent

CA 2460589

The present invention provides methods for treating individuals having a hepatitis C virus (HCV) infection, which individuals have failed to respond to therapy with an IFN-a other than consensus interferon (CIFN), or who, following cessation of therapy with an IFN-a other than CIFN, have suffered relapse. The methods generally involve a treatment regimen comprising administering a first dosing regimen of CIFN, followed by a second dosing regimen of CIFN. Ribavirin is administered with at least the second dosing regimen.

La présente invention concerne des méthodes destinées à traiter des patients atteints d'une infection par le virus de l'hépatite C (VHC), ces patients n'ayant présenté aucune réponse au traitement avec un IFN-.alpha. autre que l'interféron consensus (CIFN), ou ayant subi une rechute après cessation du traitement avec un IFN-.alpha. autre que CIFN. De manière générale, ces méthodes font intervenir un régime posologique consistant à administrer une dose de CIFN et une dose de ribavirine pendant une période déterminée, ce régime posologique permettant d'obtenir une réponse virale prolongée chez le patient.

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