Therapeutic delivery of carbon monoxide

A - Human Necessities – 61 – K

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A61K 31/28 (2006.01) A61K 33/00 (2006.01) C07F 13/00 (2006.01)

Patent

CA 2693064

Compounds, pharmaceutical compositions and methods for the therapeutic delivery of carbon monoxide to humans and other mammals that employ Mn complexes having CO ligands, and additional halogen, monodentate and/or bidentate ligands, wherein the additional ligands do not occupy trans positions relative to each other.

L'invention concerne des composés, des compositions pharmaceutiques et des procédés pour l'administration thérapeutique de monoxyde de carbone à des êtres humains et autres mammifères, qui emploient des complexes du Mn ayant des ligands CO, et un halogène supplémentaire, des ligands monodentates et/ou bidentates, les ligands supplémentaires n'étant pas en configuration trans les uns par rapport aux autres.

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