A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/44 (2006.01) A61K 31/4418 (2006.01)
Patent
CA 2248134
The present invention relates to the use of compounds of general formula (I) wherein R1 is hydrogen, halogen, lower alkyl or lower alkoxy; R2 is hydrogen; R3 is hydrogen, amino, ureido, lower alkylcarbonyl, lower alkylsulfonylamino, lower alkylcarbamoyl, carbamoyl, lower alkyloxycarbamoyl, lower alkylamino or R2 and R3 taken together are -(CH2)m-, X is methylene, hydroxymethylene, lower alkoxymethylene or carbonyl, n is 1 or 2 and m is 3 or 4; as well as pharmaceutically acceptable salts for the manufacture of medicaments for the control or treatment of diseases which represent therapeutic indications for NMDA receptor subtype specific blockers.
La présente invention se rapporte à l'utilisation de composés de la formule générale: (I) dans laquelle R?1¿ représente hydrogène, halogène, alkyle inférieur ou alcoxy inférieur; R?2¿ représente hydrogène; R?3¿ représente hydrogène, amino, uréido, alkylcarbonyle inférieur, alkylsulfonylamino inférieur, alkylcarbamoyle inférieur, carbamoyle, alkyoxycarbamoyle inférieur, alkylamino inférieur ou R?2¿ et R?3¿, réunis, représentent -(CH¿2?)¿m?-; X représente méthylène, hydroxyméthylène, alkoxyméthylène inférieur ou carbonyle, n vaut 1 ou 2 et m vaut 3 ou 4. L'invention se rapporte également à des sels pharmaceutiquement acceptables destinés à la fabrication de médicaments en vue de juguler ou de traiter des maladies représentant des indications thérapeutiques pour les agents bloquants spécifiques des sous-types des récepteurs NMDA.
Bourson Anne
Fischer Gunther
Heitz Neidhart Marie-Paule
Mutel Vincent
Trube Gerhard
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
LandOfFree
Use of 4-phenyl-3,6-dihydro-2h-pyridyl derivatives as nmda... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of 4-phenyl-3,6-dihydro-2h-pyridyl derivatives as nmda..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of 4-phenyl-3,6-dihydro-2h-pyridyl derivatives as nmda... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1447287