C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/435 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2395857
The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
L'invention concerne de nouvelles protéines. Plus spécialement, l'invention concerne des molécules d'acides nucléiques isolées qui codent pour des nouveaux polypeptides. L'invention concerne également ces nouveaux polypeptides et les anticorps qui se lient à ces derniers, ainsi que des vecteurs, des cellules hôtes et des procédés synthétiques et de recombinaison destinés à produire des polynucléotides et/ou des polypeptides humains, et des anticorps. L'invention concerne en outre des méthodes thérapeutiques et diagnostiques utiles pour diagnostiquer, traiter, prévenir et/ou pronostiquer des troubles associés à ces nouveaux polypeptides. L'invention concerne encore des procédés de criblage visant à identifier des agonistes et des antagonistes des polynucléotides et des polypeptides de l'invention. La présente invention concerne enfin des procédés et/ou des compositions permettant d'inhiber ou d'améliorer la production et la fonction des polypeptides précités.
Barash Steven C.
Rosen Craig A.
Ruben Steven M.
Barash Steven C.
Human Genome Sciences Inc.
Mbm & Co.
Rosen Craig A.
Ruben Steven M.
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