Nucleic acid and amino acid sequences involved in pain

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 29/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2457819

The present invention relates to nucleic acid sequences which are related to pain and which are differentially expressed during pain. The invention further relates to methods of identifying nucleic acid sequences which are differentially expressed during pain, microarrays comprising such differentially expressed sequences and methods of screening agents for the ability to regulate the expression of such differentially expressed sequences.

La présente invention concerne des séquences d'acides nucléiques associées à la douleur et exprimées de façon différentielle pendant la douleur. L'invention concerne en outre des méthodes d'identification de séquences d'acides nucléiques exprimées de façon différentielle pendant la douleur, des jeux ordonnés de microéchantillons comprenant ces séquences exprimées de façon différentielle, et des méthodes de criblage d'agents destinées à déterminer la capacité de réguler l'expression desdites séquences exprimées de façon différentielle.

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