Spill resistant formulations containing clays

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01)

Patent

CA 2540869

The invention relates to novel spill resistant formulations comprising either a weak base or a weak acid as the pharmaceutical ingredient, a liquid base, a clay and a water soluble cellulose ether. The clay and cellulose ether allow for a broader pH range into which the pharmaceutically active agent may be dispersed or dissolved, and therefore allows for easier preparation and formulation of the pharmaceutical composition.

L'invention concerne de nouvelles formulations résistantes au débordement, qui comprennent soit une base faible soit un acide faible comme ingrédient pharmaceutique; une base liquide; une argile et un éther de cellulose soluble dans l'eau. L'argile et l'éther de cellulose offrent une gamme de pH plus étendue dans laquelle l'agent pharmaceutiquement actif peut être dispersé ou dissout. Ils permettent donc de réaliser plus facilement une préparation et une formulation de la composition pharmaceutique.

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