Aerosol delivery of midazolam

Details Aerosol delivery of midazolam Aerosol delivery of midazolam

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 9/72 (2006.01)

Patent

CA 2152684

Midazolam, a short acting central nervous system depressant, is delivered to a patient as an aerosol spray in its base form. Preferably, midazolam is provided via a metered dose inhaler formulation which includes non-ozone depleting propellants such as 1,1,1,2-tetrafluorethane, and 1,1,1,2,3,3,3-heptapfluoropropane, together with solvents selected from the group consisting of ethyl alcohol, .alpha.-tocopherol, .alpha.-tocopherol acetate, polypropylene glycol, polyethylene glycol, lactate, diethyl ether, and dimethoxy ethane.

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