Polypeptide having an improved cytosine deaminase activity

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) C12N 9/78 (2006.01)

Patent

CA 2532783

The present invention relates to a polypeptide possessing a CDase activity, characterized in that it is derived from a native CDase by addition of an amino acid sequence with the proviso that said polypeptide has no UPRtase or Thymidine Kinase activity.

La présente invention concerne un polypeptide possédant une activité CDase, caractérisé en ce qu'il est dérivé d'une CDase native par addition d'une séquence aminoacide, à condition que ledit polypeptide ne présente pas d'activité UPRtase ou Thymidine Kinase.

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