Triazole derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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167/236, 260/313

C07D 249/08 (2006.01) A61K 31/41 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2031892

A triazole derivative is disclosed. The compound has the general formula: (see formula I) wherein R1 and R2 represent a hydrogen atom or a lower alkyl group, or R1 and R2 together form a lower alkylene group, R3 represents a lower alkyl group, and n denotes an integer of 0 to 2, provided that not both R1 and R2 are a hydrogen atom at the same time. The triazole derivatives and their salts are effective for curing or preventing deep-seated mycoses, e.g. mycotic meningitis, mycotic infectious diseases of respiratory organs, fungemia, and urinary tract mycosis.

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