Methods and compositions for the diagnosis of...

G - Physics – 01 – N

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G01N 33/573 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2266850

Disclosed are methods of detecting a gastric reflux in an extraesophageal area of a subject. Also disclosed are methods of detecting a gastric reflux disorder. The basis of the method is the detection of the presence of pepsin or pepsinogen at higher than normal levels, Detection is preferably by an immunoassay technique.

L'invention concerne des procédés de détection du reflux gastrique dans une zone extra-oesophagienne chez un sujet. Des procédés de détection d'un trouble de reflux gastrique sont également décrits. Le principe de ce procédé est la détection de la présence de pepsine ou d'un pepsinogène à des taux supérieurs à la normale. La détection s'effectue de préférence au moyen d'une technique d'immuno-essai.

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