Tetraphenylporphyn derivatives

C - Chemistry – Metallurgy – 07 – K

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C07K 7/64 (2006.01) C07D 487/22 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2116652

2116652 9307150 PCTABS00021 A hapten formed of a metalloporphyrin cofactor bound to a residue of a substrate. The hapten is designed to mimic a transition state of a metalloporphyrin catalyst and the substrate in a reaction and is characterised in that the metalloporphyrin cofactor is of formula (II), in which: R1, R2, R2', R3, R3', R8 and R8' are as defined in the specification; R4 is a bridging group connecting the metalloporphyrin catalyst to the residue of the substrate; and M is a metal ion having a co-ordination number of at least 4. Also claimed are metalloporphyrin cofactors in which R4 is H, a linker group or a removable protecting group.

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