Oxime substituted imidazo ring compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/02 (2006.01) C07D 471/06 (2006.01)

Patent

CA 2545774

Imidazo ring compounds (e.g., imidazoquinolines, 6,7,8,9- tetrahydroimidazoquinolines, imidazonaphthyridines, and imidazopyridines) with an oxime substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

L'invention concerne des composés d'un anneau d'imidazo (par exemple, des imidazoquinolines, 6,7,8,9-tétrahydroimidazoquinolines, imidazonaphthyridines, et imidazopyridines) avec un substituant d'oxime en position 2, des compositions pharmaceutiques contenant les composés, des intermédiaires et des méthodes d'utilisation de ces composés, d'une part, en tant qu'immunomodulateurs afin d'induire la biosynthèse de la cytokine chez des animaux et, d'autre part, dans le traitement de maladies, y compris, de maladies virales et néoplasiques.

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