Methods and materials relating to novel cd39-like polypeptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/55 (2006.01) A61K 38/46 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C07K 16/40 (2006.01) C07K 16/42 (2006.01) C12N 5/12 (2006.01) C12N 9/14 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2335096

The invention provides novel polynucleotides isolated from cDNA libraries of human fetal liver-spleen and macrophage as well as polypeptides encoded by these polynucleotides and mutants or variants thereof. The polypeptides correspond to a novel human CD39-like protein. Other aspects of the invention include vectors containing polynucleotides of the invention and related host cells as well as processes for producing novel CD39-like polypeptides, and antibodies specific for such polypeptides.

L'invention concerne de nouveaux polynucléotides isolés de banques d'ADNc de la rate et du foie du foetus humain et de macrophages, ainsi que des polypeptides codés par ces polynucléotides et des mutants ou des variantes de ces polypeptides. Ces derniers correspondent à une nouvelle protéine humaine semblable à CD39. D'autres aspects de l'invention concernent des vecteurs contenant ces polynucléotides et des cellules hôtes apparentées, des procédés servant à produire ces nouveaux polypeptides semblables à CD39 et des anticorps spécifiques pour ces polypeptides.

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