Immunotherapy compositions for the treatment and prevention...

A - Human Necessities – 61 – K

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Details

A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2732575

The invention relates to immunogenic peptide sequences and antibodies against said immunogenic agents for treating, preventing and/or diagnosing in human and non-human mammals a disease which is characterized by amyloid deposition, including involutive depression, confusional syndrome, dysthymia and cognitive Dysfunction Syndrome (CDS) in non-human mammals and different amyloidosis, including Alzheimer's disease in humans. Moreover, the invention provides diagnostic methods for the above diseases using the antibodies of the invention.

La présente invention concerne des séquences peptides immunogènes et des anticorps dirigés contre ces agents immunogènes, permettant de traiter, prévenir et/ou diagnostiquer, chez les humains et les mammifères non humains, une affection caractérisée par le dépôt d'amyloïdes, et notamment la dépression involutive, la dysthymie, et, chez les mammifères non humains le syndrome de dysfonctionnement cognitif, mais aussi différentes amyloses dont notamment, chez les humains, la maladie d'Alzheimer. L'invention concerne en outre des procédés utilisant les anticorps de l'invention pour diagnostiquer les affections mentionnées.

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