Anti-hypertensive compositions of secondary amine-nitric...

Details Anti-hypertensive compositions of secondary amine-nitric... Anti-hypertensive compositions of secondary amine-nitric...

A - Human Necessities

61

K

A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07C 291/08 (2006.01) C07C 307/02 (2006.01) C07D 295/28 (2006.01)

Patent

CA 2066409

This invention concerns anti-hypertensive compositions and a method of lowering blood pressure in mammals. The active component of the compositions is a compound of formula (1), wherein R1 and R2 are independently chosen from straight chain and branched chain C1-C12 alkyl groups and benzyl, with the proviso that no branch occur on the alpha carbon atom of the alkyl groups; or R1 and R2 together with the nitrogen atom are bonded to form a pyrrolidino, piperidino, piperazino or mor- pholino group M + x is a pharmaceutically acceptable cation, wherein x is the valence of the cation.

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