A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/06 (2006.01) A61K 31/40 (2006.01)
Patent
CA 2426592
This invention relates to pharmaceutical compositions comprising combinations of a statin, a prodrug thereof or a pharmaceutically acceptable salt of said statin or said prodrug and a sorbitol dehydrogenase inhibitor, a prodrug thereof or a pharmaceutically acceptable salt of said sorbitol dehydrogenase inhibitor or said prodrug, kits containing such combinations and methods of using such combinations to treat mammals, including humans, suffering from arteriosclerosis and/or diabetic complications such as diabetic neuropathy, diabetic nephropathy, diabetic cardiomyopathy, diabetic retinopathy, diabetic microangiopathy, diabetic macroangiopathy, cataracts or foot ulcers.
La présente invention concerne des compositions pharmaceutiques contenant des combinaisons d'une statine, d'un promédicament à base de statine ou d'un sel acceptable pharmaceutiquement de ladite statine ou dudit promédicament et un inhibiteur de sorbitol-déshydrogénase, un prodrogue à base dudit inhibiteur ou d'un sel pharmaceutiquement acceptable dudit inhibiteur de sorbitol-déshydrogénase ou dudit promédicament. L'invention concerne également des kits contenant de telles combinaisons et des méthodes d'utilisation desdites combinaisons dans le traitement des mammifères, y compris les humains, souffrant d'athérosclérose et/ou de complications diabétiques telles que la neuropathie diabétique, la néphropathie diabétique, la cardiomyopathie diabétique, la rétinopathie diabétique, la microangiopathie diabétique, la macroangiopathie diabétique, les cataractes ou les ulcères du pied.
Pfizer Products Inc.
Smart & Biggar
LandOfFree
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