Method of controlling proliferation and differentiation of...

A - Human Necessities – 01 – N

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A01N 1/02 (2006.01) C12N 5/071 (2010.01) C12N 5/0789 (2010.01) A61K 35/12 (2006.01) C12N 15/87 (2006.01) A61K 48/00 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2320073

A method of expanding a population of cells, while at the same time inhibiting differentiation of the cells, the method includes the step of providing the cells with conditions for cell proliferation and, at the same time, for reducing a capacity of the cells in utilizing transition metals. The method can be executed both in vivo and ex vivo.

L'invention concerne un procédé d'extension d'une population de cellules, qui inhibe en même temps la différenciation de ces cellules, ce procédé comprenant l'étape consistant à préparer les cellules au moyen de conditions favorisant la prolifération cellulaire et en même temps réduisant une capacité des cellules à utiliser des métaux de transition. On peut exécuter ce procédé à la fois in vivo et ex vivo.

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